By default, Matplotlib uses a floating point representation of time in days since the epoch, so plotting data with microsecond time resolution does not work well for dates that are far (about 70 years) from the epoch (check with :None:None:`~.dates.get_epoch`).
If you want sub-microsecond resolution time plots, it is strongly recommended to use floating point seconds, not datetime-like time representation.
If you really must use datetime.datetime() or similar and still need microsecond precision, change the time origin via :None:None:`.dates.set_epoch` to something closer to the dates being plotted. See :None:doc:`/gallery/ticks/date_precision_and_epochs`.
Make ticks on regular intervals of one or more microsecond(s).
The following pages refer to to this document either explicitly or contain code examples using this.
matplotlib.dates
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